\documentclass{article}

 

\usepackage{amsmath}

 

\begin{document}

 

\begin{align}
               111 &\bullet 222\\
               &\bullet 333 \begin{aligned}[t]
                              444 &\bullet 555\\
                              666 &\bullet 777
               \end{aligned}\\
               &\bullet 888\\  
\end{align}

\end{document}
